The System Center Management service terminated with service-specific error %%-2147467259
I had the following issue on one of my servers
“The System Center Management service terminated with service-specific error %%-2147467259” when I wanted to start my Healthservice.

When searching the internet I found the following blogpost http://blogs.technet.com/b/smsandmom/archive/2008/04/30/opsmgr-2007-healthservice-service-fails-to-start-with-25362-warning.aspx . The blogposts says that the State directory registry key can be corrupt but that was fine in my case.
But at the end of the blogpost I found my solution:
This error can be caused by the WindowsAccountLockDownSD Key in at HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\HealthService\Parameters\Management Group\<Management Group Name Here> being invalid or non-present. And indeed, that was my issue: the WindowsAccountLockDownSD Key was missing on my server.

The easiest way to resolve the issue with the Windows AccountLockDownSD key is to export the registry key from a similar, working system and then import it in to the registry of the server experiencing the problem. Once this is complete the HealthService should start successfully.

thanks,
Alexandre Verkinderen